People


Matías Palumbo

PhD student

Matías joined the Metzis Lab as a PhD student in September 2025. He completed a five-year integrated Master’s in Mathematics at the National University of Rosario in 2024.

Now, Matías is researching the transcriptional control mechanisms that underlie cell fate decisions during neural crest development, with a focus on developing and applying mathematical models to gene regulatory networks.

Matías is co-supervised by Omer Karin in the Department of Mathematics, Imperial.

Email: MATIAS PALUMBO


Edyta Walewska

Postdoctoral Scientist

Edyta completed her PhD in the António Galvão’s lab at the Polish Academy of Sciences in Olsztyn, where she investigated how maternal obesity alters the uterine environment, with a particular focus on the role of leptin signalling in impaired decidualisation and placental development (10.1007/s00018-024-05336-7; 10.1530/REP-24-0319). This led to her PhD being awarded by the Medical University of Białystok.

She then joined Gavin Kelsey’s group at the Babraham Institute as a research assistant, contributing to a study on oocyte competence and epigenetic regulation. Now in the Metzis lab, Edyta is investigating how retinoic acid signalling shapes cell identity, with a focus on transcriptional repression.

Email: EDYTA WALEWSKA


Lok Ting Nick New (Nick)

PhD student

Nick joined the Metzis Lab as a PhD student in October 2024. He obtained a BA in Biological Natural Sciences at the University of Cambridge, where he undertook his final year project in the Ferguson-Smith Lab, studying how cis-regulatory elements contribute to imprinted gene expression. In 2024, Nick completed an MPhil in Genetics at the University of Cambridge in the Steventon Group, investigating the role of Cdx4 in zebrafish segmentation.

Now, Nick is researching how Cdx factors influence chromatin accessibility and regulate cell identity during spinal cord development.

Email: NICK NEW


Christos Kalaitzis

PhD student

Christos obtained a BSc (Hons) in Genetics from the University of Sussex in 2019. He completed an MSc in Human Molecular Genetics at Imperial College London in 2020, where his final project in the Lovell-Badge lab at the Francis Crick Institute focused on the transcription factor FOXL2 in craniofacial development and adult pituitary hormonal lineage specification.

Staying at the Crick, Christos then worked as a Laboratory Research Officer with the Briscoe lab, where he studied the molecular mechanisms of how cis-regulatory elements work to direct gene expression in the developing spinal cord. 

In 2022, Christos joined the Metzis lab at Imperial College London as a SAMURII PhD student. In collaboration with the Vaquerizas lab, he is examining how cell identity is controlled during neural crest development.

Email: CHRISTOS KALAITZIS


Irène Amblard

Research Associate

Irène graduated from École Polytechnique (Paris, France), followed by a PhD in cell biology at Sorbonne Université. Under the supervision of Alain Joliot at the Collège de France, she developed expertise in protein trafficking and cell signalling. Her work focused on the mechanisms controlling protein trafficking, and how these events impact the establishment of signalling gradients in developing tissues. See some of her work highlighted in the Journal of Cell Science.

Irène joined the Metzis Lab in February 2021 to study how regulatory elements impact transcription factor dynamics and cell identity during development.

Email: IRÈNE AMBLARD


Vicki Metzis

Lab head

Vicki Metzis is a developmental biologist. She obtained her PhD from the University of Queensland, working with Carol Wicking at the Institute for Molecular Bioscience in Brisbane. Here, she developed an interest in mouse genetics and in vitro approaches to study gene regulatory networks.

Vicki then undertook postdoctoral training in the lab of James Briscoe at the Francis Crick Institute, where she developed expertise in the use of embryonic stem cells to model cell fate decisions, combining experimental and computational approaches.

In 2020, Vicki moved to Imperial College London to establish her own research group, which studies the molecular mechanisms that control cell identity during development. Vicki is a Sir Henry Dale Fellow supported by Wellcome and The Royal Society.

Email: VICKI METZIS


Lab alumni


Hayden McCarthy

MRes student

Hayden completed an MMath (hons) mathematics degree at the University of Manchester in 2021 before spending three years working in the civil engineering industry. After developing an interest in life sciences he then enrolled in an MRes in Bioinformatics and Theoretical Systems Biology at Imperial.

In 2025, Hayden completed an MRes research project in the Metzis lab, applying in silico approaches to predict cis-regulatory element function, in collaboration with Juanma Vaquerizas.

In October 2025, Hayden began his PhD in the LIDo programme.

Email: HAYDEN MCCARTHY


Lorraine Olagne

MSc student

Lorraine joined the Metzis Lab in April 2024. She is enrolled at the engineering school of École Polytechnique (Paris, France), where she has studied molecular and cellular biology, as well as neurosciences and immunology.


In the Metzis Lab she completed an MSc project on the extrinsic cues regulating the dynamics of CDX transcription factor expression using in vitro models of neuromesodermal progenitors.

Email: LORRAINE OLAGNE


Julia Needham

PhD student

Julia joined the Metzis Lab at Imperial College London as a PhD student in 2020. She obtained a BSc in Biology from the the University of Bristol in 2019. She completed an MPhil in Genetics at the University of Cambridge in the Ferguson-Smith Lab, studying the epigenetic regulation of the mammary gland. She is funded by the President’s PhD Scholarship.

Julia completed her PhD in October 2024 and is now working at The Francis Crick Institute as the Quality and Governance Manager for the MANIFEST Consortium (https://www.manifest-io.org.uk).

Email: JULIA NEEDHAM


Yuewen Zhong

MSc student

Yuewen is an MSc student in Applied Genomics at Imperial College London. She completed her bachelor’s degree in Animal Science at the University of California, Davis, where she undertook interdisciplinary coursework such as physiology, reproductive biology and molecular biology. In March 2023, she joined the Metzis’s lab to conduct research for her MSc project. Her project focused on employing computational approaches to investigate gene regulatory networks operating during development through the analysis of high throughput single cell sequencing data. Yuewen is now a research assistant at the University of Hong Kong.

Email: YUEWEN ZHONG


Jia Luo

MSc student

Jia obtained her BSc in Biomedicine at University of East Anglia in 2022 and is currently enrolled in the Reproductive and Developmental Biology MSc program at Imperial College London. Her interest in developmental biology really grew after completing an undergraduate lab project investigating HOXC6 target genes operating at the cervical to thoracic boundary in chick embryos at the Münsterberg lab.

Jia finds the process of how cells interpret positional information and gain a specific fate during embryonic development an interesting question and took this curiosity further in her project in the Metzis lab, looking at the regulation of CDX2 during embryonic development.

Email: JIA LUO


Karlie Zhang

MSc student

Karlie graduated from Tianjin Medical University (Tianjin, China) in 2017, followed by a resident training program in Tianjin General Hospital. She is now an MSc student in the Reproductive and Developmental Biology Programme at Imperial College London, and has joined the lab for her project focusing on the expression and function of CDX2 during mouse development. She’s interested in reproductive tract inflammation, fertility-sparing treatment in Gynecology Oncology, as well as embryo development. 

Email: KARLIE ZHANG


Jihye Song

BSc student

Jihye is studying a BSc in Medical Biosciences at Imperial College London.

Jihye joined the Metzis Lab during July-September 2022 to develop experience in genome engineering approaches and their application to embryonic stem cells. She has a broad range of interests spanning regenerative medicine, cell fate decisions, organogenesis and immunology.

Email: JIHYE SONG


Rufus Morgan

BSc student

Rufus has an interest in developmental biology and completed a “hybrid” summer project in the lab during his BSc.

Rufus joined the Metzis Lab during July-September 2021 to examine the role of Hox genes in spinal cord development (read more about his experiences on the node). His project was supported by the British Society for Developmental Biology Gurdon / Company of Biologists Studentship scheme. Rufus is currently completing his Medical Biosciences BSc at Imperial College London supported by an Imperial Presidents scholarship.

Email: RUFUS MORGAN


Neda Mousavy

Research Associate

Neda obtained her BSc in Biology from Iran. She then moved to London where she undertook an MSc in Molecular Medicine at UCL. She continued her scientific career working as a Research Assistant at the UCL-Institute of Child Health and at the National Institute for Medical Research (now part of The Francis Crick Institute). During these years she developed expertise in neural tube and pituitary gland development, working with James Briscoe and Juan Pedro Martinez-Barbera. She was supported by a Diabetes UK grant to pursue her PhD at Imperial College London. Her work focused on the roles of two GWAS genes linked to type 2 diabetes in the control of glucose homeostasis. Neda joined the Metzis Lab as a Research Associate working on neuroaxis development. She is now based at Sixfold Bioscience, at our neighbouring White City Campus.

Email: NEDA MOUSAVY


*JOIN OUR TEAM*

If you are interested in joining the Development and Transcriptional Control group, located at the  London Institute of Medical Sciences (LMS) at Imperial College London, contact us to discuss your interests and explore opportunities to join our team!


Postdoctoral Fellowships

Email enquiries are welcome from applicants wishing to apply for postdoctoral fellowship opportunities related to the group’s core interests.

Applicants are encouraged to check the deadlines for submission and eligibility criteria for further details prior to getting in touch.


President’s PhD Scholarship at Imperial College London

These positions suit applicants interested in developing expertise in stem cell technologies, molecular biology and mouse genetics. For further details on the PhD programme, including entry requirements and application due dates, see below:


MRC DTP Studentships at Imperial College London

Enquiries are currently welcome from students wishing to apply to the MRC DTP program at Imperial College London. This program would suit applicants wishing to pursue a cutting edge project spanning development, stem cells and regenerative medicine. For further details on the programme, including entry requirements and due dates, see below: