Development & Transcriptional Control


We study how diversity in cell identity arises during embryonic development.

Discovering the molecular basis of cellular diversity

As an embryo develops, a wide variety of cell types form along the length of the body. This diversity is dependent on position: some cell types form exclusively in the head, while others form in the trunk. Our ambition is to understand how this organisation is established and maintained during development. Combining experimental and dry lab approaches, we are investigating how cells develop into different lineages, and how this is encoded in the structure and function of the genome.

By developing strategies to engineer precise tissues from embryonic stem cells, it is our hope that we will contribute valuable insights for regenerative medicine and the future of disease modelling.


Development & Transcriptional Control Group

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Vicki Metzis, Lab Head

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Imperial College London
Hammersmith Campus

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